URINARY 17-KETOSTEROID CONJUGATES IN HIRSUTISM
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منابع مشابه
URINARY 17 - KETOSTEROID CONJUGATES IN HIRSUTISM By PIERRE MAUVAIS - JARVIS AND ETIENNE - EMILE BAULIEU
The principal urinary 17-ketosteroids (17KS) were analyzed in 16 cases of hirsutism; their conjugated forms were separately cleaved, and the liberated 17KS were chromatographed and quantitated. Six were clinically classified as cases of Stein-Leventhal syndrome and the remaining 10 as "idiopathic hirsutism." 1 The following conditions were excluded a priori: adrenal and ovarian tumors, Cushing'...
متن کاملIsolation of urinary 17-ketosteroid conjugates by ammonium sulfate precipitation.
Ammonium sulfate precipitation of urinary 17-ketosteroid conjugates is a rapid, effective method for isolating and purifying them. Negligible quantities of pigment are produced during acid hydrolysis of solutions of the precipitated conjugates. Despite elimination of nonspecific chromogenic material, colorimetric determinations of Zimmerman chromogens with use of the Allen correction of absorba...
متن کاملCharacteristics of a 17-ketosteroid reaction.
An improved method for the determination of 17-ketosteroids is described, which involves an increase in sensitivity by the simple expedient of upsetting the equilibrium of the reaction in removing the products of reaction by precipitating the chromophore formed. This precipitation system appears to achieve about 1.6 times the color sensitivity for the same reaction carried out as a solution pro...
متن کاملEffect of Cortisone on 17-Ketosteroid Excretion *
In 1952 cortisone therapy was initiated in two patients with far advanced prostatic carcinoma.2 As part of the study of those patients, determinations were made of urinary 17-ketosteroid excretion before and during therapy with cortisone. Rather large increases in excretion of 17-ketosteroids were noted during the administration of high doses of cortisone in both patients. This unexpected findi...
متن کاملGold therapy and neutral 17-ketosteroid excretion in rheumatoid arthritis.
Although the striking benefits of the administration of cortisone and ACTH in rheumatoid arthritis have been widely publicized, the exhibition of gold salts still retains an important place in the therapy of some types of case. The manner in which gold salts act is not known, but has been ascribed to stimulation of the reticulo-endothelial system, some alteration in the immunological or enzymat...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1962
ISSN: 0021-9738
DOI: 10.1172/jci104626